DIFFERENTIAL AFFINITY CHROMATOGRAPHY COUPLED TO MASS SPECTROMETRY: A SUITABLE TOOL TO IDENTIFY COMMON BINDING PROTEINS OF A BROAD-RANGE ANTIMICROBIAL PEPTIDE DERIVED FROM LEUCINOSTATIN

Leucinostatins are antimicrobial peptides with a broad range of activities against infectious agents as well as mammalian cells.The leucinostatin-derivative peptide ZHAWOC_6027 (peptide 6027) was tested in vitro and in vivo for activity against the intracellular apicomplexan parasite Toxoplasma gondii.While highly efficacious in vitro (EC50 = 2 nM)

In this study, we investigate the effectiveness of perceptual training, administered to Argentinean learners, in the perception and production of word-initial voiceless Chillum stops in English.24 participants were divided into 3 groups: (i) Group 1, which participated in 3 training sessions; (ii) Group 2, which, besides performing the same trainin

Currently, no rabies virus-specific antiviral drugs are available.Ranpirnase has strong antitumor and antiviral properties associated with its ribonuclease activity.TMR-001, a proprietary bulk drug substance solution of ranpirnase, was evaluated against rabies virus in three cell types: mouse neuroblastoma, BSR (baby hamster kidney cells), and bat